Ack kinase regulates CTP synthase filaments during Drosophila oogenesis

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Ack kinase regulates CTP synthase filaments during Drosophila oogenesis.

The enzyme CTP synthase (CTPS) dynamically assembles into macromolecular filaments in bacteria, yeast, Drosophila, and mammalian cells, but the role of this morphological reorganization in regulating CTPS activity is controversial. During Drosophila oogenesis, CTPS filaments are transiently apparent in ovarian germline cells during a period of intense genomic endoreplication and stockpiling of ...

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ژورنال

عنوان ژورنال: EMBO reports

سال: 2014

ISSN: 1469-221X,1469-3178

DOI: 10.15252/embr.201438688